APEA Predictor Exam 2023 Questions and Answers(Verified Answers)

What is the recommended treatment for cat scratch disease?
usually self-limiting and presents with lymphadenopathy that goes away on it’s own; severe cases may benefit from azithromycin

What is the most common cause of traveler’s diarrhea?
e coli

What bacteria is responsible for causing cat scratch disease?
bartonella henselae

What are the 4 different components of tetralogy of fallot?
overriding aorta, pulmonary stenosis, right ventricular hypertrophy, and a ventricular septal defect

What does the murmur auscultated in tetralogy of fallot sound like?
systolic murmur best heard at the left upper sternal border

What does the murmur auscultated in a ventricular septal defect sound like?
systolic murmur best heard at the left lower sternal border

Where is the aorta best auscultated?
at the second ICS to to the right of the sternum

Where is the pulmonary artery best auscultated?
at the second ICS to the left of the sternum

What is a scotoma?
a blind spot or aura that obstructs part of your vision

Is presbyopia nearsightedness or farsightedness?
farsightedness meaning it can be harder to see things up close, such as reading a newspaper and may need to hold it farther away or use reading glasses

Is myopia nearsightedness or farsightedness?
nearsightedness meaning it is hard to see things far away

Do cataracts cause myopia or presbyopia?
myopia; meaning nearsightedness and they make things blurry that are farther away which is why driving at night becomes difficult

What is the USPSTF’s recommendation on scoliosis screening for adolescents?
insufficient

When should adolescent girls be screened for scoliosis?
as early as 10 years old and then again at age 12

When should adolescent boys be screening for scoliosis?
between age 12-13

What is Auspitz sign?
the appearance of small bleeding points after successive layers of scale have been removed from the surface of psoriatic papules or plaques

A positive Auspitz sign is indicative of what?
psoriasis

When are pregnant women screening for gestational diabetes?
week 24-28

What is round ligament pain?
a deep, sharp, stabbing or stretching sensation that begins or worsens with movement and can be unilateral or bilateral. This is a normal and benign part of pregnancy

What are the components of the fetal biophysical profile?
nonstress test (heart rate monitoring), amniotic fluid analysis, fetal movements, fetal tone, and fetal breathing

How is the fetal biophysical profile performed?
via ultrasound and fetal heart rate monitoring

When is the fetal biophysical profile often performed?
in the third trimester, often after week 28-32

What is a normal kick count in pregnancy?
at least 10 kicks in a consecutive two hour period

How much weight should an underweight woman gain in pregnancy?
28-40 pounds

How much weight should a normal weight woman gain in pregnancy?
25-35 pounds

How much weight should an overweight woman gain in pregnancy?
15-25 pounds

How much weight should an obese woman gain in pregnancy?
11-20 pounds

Underweight and normal weight woman should be gaining how much weight per week in their second and third trimesters?
1 pound

Overweight and obese women should be gaining how much weight per week in their second and third trimesters?
0.5 pounds

What is the biggest risk associated with scabies?
secondary infection due to itching

What do scabies look like on the skin?
red papular bumps that have s shaped burrows on them; may have fluid coming from them

Sickle cell anemia is what type of anemia?
normocytic

How is sickle cell anemia diagnosed?
hemoglobin electrophoresis

Which age group is rheumatic fever most common in?
children ages 5-15

What are the major symptoms of rheumatic fever?
carditis, arthritis, chorea, erythema marginatum (rash), subcutaneous nodules

What are the minor symptoms of rheumatic fever?
fever, elevated ESR, prolonged PR interval

How do we treat rheumatic fever?
refer to the hospital

What is chorea?
abnormal involuntary movements

What are the main s/s of rubeiola (measles)
Koplick spots + the 3 c’s – cough, coryza, conjunctivitis

GABHS infection puts individuals at the highest risk of developing what sequelae?
peritonsillar abscess, glomerulonephritis, rheumatic fever

What is the diagnostic criteria for acute rheumatic fever?
2 major criteria OR 1 major + 2 minor criteria PLUS evidence of a recent strep infection

When can a breastfeeding mother breast feed again after drinking alcohol?
wait 2-3 hours per drink consumed before breastfeeding again

Can a mother take methadone while pregnant and breastfeeding?
yes

Does subsequent mean before or after?
after

What is the recommended treatment for Kawasaki disease?
refer to the ED, will likely need IVIG and high dose aspirin

What are the s/s of Kawasaki disease?
fever + CREAM (conjunctivitis, rash, erythema of palms and soles, adenopathy cervical, mucous membranes)

Kawasaki disease is caused by what?
an acute vasculitis of the small and medium blood vessels

What is the main difference between Kawasaki disease and scarlet fever?
KD has conjunctivitis and scarlet fever does not

The rash associated with acute rheumatic fever
erythema marginatum

The rash associated with parvovirus aka slapped cheek aka fifth disease
erythema infectiosum

What does erythema marginatum of rheumatic fever look like?
erythematous with a central clearing, not itchy

The medical term for tennis elbow
lateral epicondylitis

What is the leading cause of death in anorexia?
suicide

Erikson stage from birth to 18 months
trust vs mistrust

Erikson stage from 18 months to 3 years
autonomy vs shame and doubt

Erikson stage from 3-5 years
initiative vs guilt

Erikson stage from 5-13 years
industry vs inferiority

Erikson stage from 13-21 years
identity vs role confusion

Erikson stage from 21-39 years
intimacy vs isolation

Erikson stage from 40-65 years
generativity vs stagnation

Erikson stage for 65 and older
ego integrity vs despair

Macrobid/nitrofurantoin is contraindicated in which patients?
those with renal insufficiency

Treatment options for complicated UTI
cipro or levo x 5-7 days

Treatment options for uncomplicated UTI
bactrim x 3 days, macrobid x 5 days, fosfamycin 1g one time dose

Olecranon bursitis is pain in which region of the elbow?
the posterior elbow; will also have swelling and warmth

Lateral epicondylitis manifests as what type of elbow pain?
weak grip and pain with gripping, pain with rotation of the wrist and forearm

The medical term for golfer’s elbow
medial epicondylitis

How does the pain in lateral vs. medial epicondylitis differ?
lateral epicondylitis is worse with supination of the hand and medial epicondylitis is worse with pronation of the hand

involves tapping a finger along the problem nerve
tinel sign

asking the patient to place both elbows on a table while keeping both forearms vertical and flexing both wrists
phalen sign

Which nerve runs on the side of the thumb
median nerve

Which nerve runs on the side of the pinky finger
ulnar nerve

What is ankylosing spondylitis?
an inflammatory condition affecting the spine causing chronic back pain and stiffness that improves with exercise and enthesitis

What is the treatment for ankylosing spondylitis?
refer to rheumatology for possible DMARDs

What are the s/s of polymyalgia rheumatica?
chronic pain in the proximal joints (shoulders and hips) bilaterally with stiffness lasting for more than 45 minutes

What is the recommended treatment for polymyalgia rheumatica?
PO steroids and refer to Rheumatology to confirm the diagnosis

Where are the biggest food sources of vitamin B12?
fish, meat, poultry, eggs, and dairy products, also fortified breakfast cereals and fortified nutritional yeasts

What is the gold standard for the diagnosis of herpes?
nucleic acid amplification test

Most cases of acute sinusitis are viral and how can we treat them?
treat the symptoms with intranasal steroids and saline rinses

What is the difference between chronic vs gestational hypertension?
chronic htn is present before 20 weeks gestation or 12 weeks after delivery; gestational hypertension is after 20 weeks gestation

Which is the recommended diagnostic when a patient has a breast lump?
if less than 45, do an ultrasound. if older than 45, do a diagnostic mammogram.

An overactive bladder is what type of incontinence?
urge incontinence

What is the recommended treatment for urge incontinence?
anticholinergics like oxybutynin

What is the recommended treatment for stress incontinence?
alpha agonists like sudafed, TCAs

What is the recommended treatment for BPH?
alpha blockers like terazosin, doxazosin, tamsulosin

Alcohol and marijuana worsen which type of incontinence?
urge

Which SSRI is safest in pregnancy? Which poses the most risk?
sertraline; paroxetine

Infants born to women who smoke are at increased risk for what?
low birth weight and preterm delivery

What is the best marker of an acute MI?
troponin

When do troponins peak after a MI?
12 hours

When should an infant be able to display a conjugate gaze (track you all the way across the room)?
6 months

Which medication is approved in Peds for the prevention of febrile seizures?
diazepam

Folic acid is which vitamin?
vitamin B9

What is the dosage preferred for folic acid deficiency?
1-5mg daily

Dosage of folic acid in pregnancy to prevent neural tube defects
400mcg daily

What are ECG changes you may see on a patient with hypokalemia?
tachyarrhythmas, ST depression, prolonged QT, and U wave present

What are ECG changes you may see on a patient with hyperkalemia?
peaked T waves

A U wave present on EKG is thought to represent what?
repolarization of the purkinje fibers

What is considered legal blindness?
20/200 or worse

What is the pain of temporal arteritis like?
new onset headache, jaw pain with chewing

Are nexplanon and norplant (levonorgestrol) combined contraceptives or progesterone only?
progesterone only

Breastfeeding women cannot have which type of anti-contraceptive?
anything with estrogen in it; this includes things like cocps

When should pediatrics be screened for hyperlipidemia?
between 9 and 11 years old

What is the tell-tale symptom of endometriosis?
progressive dysmenorrhea

What is treatment for first-line endometriosis?
cyclic OCPs and NSAIDs

How is endometriosis diagnosed?
via transvaginal ultrasound

What are risk factors for the development of cervical cancer?
HIV, immunocompromised, low socioeconomic status, smoking, hispanic, DES daughters, long term contraceptive use

What does the D in melanoma stand for?
greater than 6mm in diameter or 1/4 of an inch

Boutonniere deformities are indicative of what disease?
rheumatoid arthritis

What are the potassium sparing diuretics?
spironolactone, triamterene, amiloride, eplenerone

What class of diuretic is bumetanide?
a loop diuretic, same as lasix

What is Chovstek’s sign?
a contraction of ipsilateral facial muscles subsequent to percussion over the facial nerve, indicative of hypocalcemia

What is Trousseau’s sign?
a carpopedal spasm induced by ischemia secondary to the inflation of a sphygmomanometer cuff, indicative of hypocalcemia

Calcium is in an inverse relationship with what electrolyte?
phosphorous

When you see the trigger word “christmas tree”, what rash should you consider?
pityriasis rosea

What is the recommended treatment for pityriasis rosea?
nothing; it is a viral rash and can last up to two months before clearing on it’s own

Causing harm or damage
deleterious

How do you calculate ideal body weight for men?
start at 106 pounds and then add 6 for every inch above 5 feet

How is lichen sclerosus treated?
topical steroids, topical calcineuronin inhibitors to suppress the immune system, topical or oral retinoids, phototherapy

What is the tell-tale sign of malignant hypertension?
retinopathy and blurred vision; characterized by a diastolic BP of greater than 130

What is the difference between a Parkinsonian tremor and an essential tremor?
a Parkinson tremor is also known as a resting tremor and is seen at rest, may look like pill-rolling. an essential tremor is bilateral, symmetric and seen when the hands are doing something

What can worsen and improve an essential tremor?
worsened by stress or fatigue, improved by alcohol

What is first-line treatment for trigeminal neuralgia?
carbamazepine (tegretol) or amtriptyline

Are Parkinsonian tremors unilateral or bilateral at first?
unilateral

Where is the TMJ best palpated?
anterior to the tragus

What are the primary bacteria in dog bites?
staph, strep, and pasteurella

What is the gold standard treatment of giant cell arteritis?
oral steroids and potential artery biopsy by rheum

Who is a candidate for Truvada for Prep?
if you are an IV drug user, have had a sexual partner with HIV in the last 6 months, do not consistently use a condom and engage in anal or vaginal sex, or have been diagnosed with a STD in the last 6 months

Post exposure prophylaxis for someone with HIV should be completed when?
within 72 hours of the exposure

Who should be screened for HIV?
everyone at least once from age 13-64 if low risk, and then more frequently if high risk

Should patients undergo gonorrhea testing to confirm a cure after receiving treatment?
only if they had pharyngeal gonorrhea, not vaginal or anal

Tanner stage 1 female breast developmental
prepubertal

Tanner stage 2 female breast development
thelarche; the breasts bud as a small mound and the areola increases in diameter

Tanner stage 3 female breast development
the areola, breast, and nipple grow together in one mount

Tanner stage 4 female breast development
the areola and nipple separate from the breast to form a secondary mound

Tanner stage 5 female breast development
mature nipples project only

Tanner stage 1 male genital development
prepubertal

Tanner stage 2 male genital development
testicles and scrotum enlarge

Tanner stage 3 male genital development
testicles continue to enlarge and the penis lengthens

Tanner stage 4 male genital development
penis lengthens, testicles enlarge, and the scrotum darkens

Tanner stage 5 male genital development
mature

Antibiotic of choice for lyme disease
doxycycline

Antibiotic of choice for cellulitis
keflex or cefdinir

Antibiotic of choice for chlamydia
azithromycin

Antibiotic of choice for syphilis
penicillin G

Antibiotic of choice for bacterial vaginosis
flagyl

Antibiotic of choice for trichomoniasis
flagyl

Antibiotic of choice for acute prostatitis
cipro (or ceftriaxone if STI related)

Antibiotic of choice for PID
ceftriaxone and doxycycline

Antibiotic of choice for pyelonephritis
cephalexin or bactrim

Antibiotic of choice for MRSA
bactrim, clindamycin, doxycycline

Antibiotic of choice for dog or cat bite
augmentin

Antibiotic of choice for mastitis
keflex

Antibiotic of choice for chronic bacterial prostatitis
bactrim plus cipro or levo

What is the earliest sign of diabetic nephropathy on labwork?
microalbuminuria in the urine

Recommended treatment for verruca (warts)
topical salicylic acid daily x 12 weeks

Perineal pain is indicative of what in males?
prostatitis

Gestational diabetes screening occurs between what weeks gestation?
24-48

When you ask the patient to take a deep breath in and then palpate over the RUQ abdomen. Positive when pain is elicited. This is a sign of _.
Murphy’s sign; cholecystitis

What are names of LABA medications?
salmeterol

What is encopresis in children?
stool incontinence after the age of being toilet trained

The medical term for being cross-eyed
strabismus

What is atopic dermatitis?
eczema

Tests used to diagnose developmental hip dysplasia
Barlow and Ortolani maneuvers

What is the female athlete triad?
disordered eating, amenorrhea, osteoporosis

How do patients with aortic regurgitation typically present?
they will have a long asymptomatic period followed by exercise intolerance, then dyspnea at rest. The left ventricle eventually fails unless the aortic valve is replaced.

What does the rash of fifth disease (a viral exanthem) look like?
maculopapular rash that blanches easily and may be accompanied by joint aches

What cardiac abnormalities are expected to be heard on auscultation of a pregnant patient?
a venous hum murmur and an S3

When a headache accompanies a stroke, is this most often hemorrhagic or ischemic?
hemorrhagic

AV nicking is most commonly seen on retinal exam of which chronic condition?
hypertension

Within 6 months of being started on a TCA or SSRI, what is a common side effect that occurs?
weight gain

When does otitis media with effusion usually occur?
either before or after an episode of acute otitis media. This effusion is not infected fluid but it is considered a breeding ground for bacteria. This should not be treated with antibiotics.

The medical term for jock itch
tinea cruris

Tinea cruris “jock itch” is a common __ infection and should be treated with what?
fungal; OTC antifungal cream

What are teaching points for males to avoid contracting tinea cruris?
dry off after swimming and don’t stay in a wet bathing suit

Tinea cruris can affect the inner thighs but never what else?
the penis or scrotum

On microscopic exam, what is most likely to be seen in the presence of a bacterial infection?
cocci and rods

On microscopic exam, what is most likely to be seen in the presence of a candidal infection?
yeasts

What are dermatophytes?
fungi

On microscopic exam, what is most likely to be seen in the presence of a dermatophytic (fungal) infection?
hyphae that are long, thin, and branching (such as in the case of tinea pedis, tinea cruris, and tinea corporis)

The medical term for ringworm
tinea corporis

What is the most common cause of viral pneumonia in peds?
RSV

Viral pneumonia is the most common type of pneumonia in children of what ages?
6 months to 5 years

What is the simplest way to screen for nutritional adequacy in older adults?
measure their weight

How are scabies treated?
via permethrin and good hygiene

What are common side effects of NSAIDs?
renal impairment, acute renal failure, gastritis

What is the most common cause of pernicious anemias?
vitamin B12 deficiency

How should oral iron supplements be taken?
on an empty stomach with something acidic and high in calcium such as orange juice

Group A strep pharyngitis can be accompanied by what symptoms other than the classic Centor criteria?
abdominal pain, nausea, and vomiting

A stool specimen that is positive for WBCs is a sign of what?
a viral or bacterial infection

The only type of incontinence that would not benefit from pelvic floor therapy is what?
overflow incontinence

What do the skin manifestations of a penicillin allergy look like?
hives

What are symptoms that someone will experience as soon as they are started on a SSRI and when will this resolve?
headache, nausea, insomnia, restlessness, agitation; will resolve in 2 weeks

What causes the dry cough in people taking an ACEI?
the buildup of bradykinin which is usually degraded by ACE

ACEI induced coughs usually begin how soon after starting the medication?
within 2 weeks

COPD is often associated with what sequelae?
anxiety and depression

When should an antiviral be started in a patient with shingles?
within 72 hours of the onset of symptoms

What is the drug of choice for treating UTIs in male patients?
bactrim for 7-10 days

What is the leading cause of CKD and ESRD in the united states?
diabetes

What is the usual recommendation about administering MMR and varicella immunizations?
they should be given on the same day or at least one month apart

What are the classic symptoms of an atopic pregnancy?
amenorrhea, vaginal bleeding, abdominal pain

What is sideroblastic anemia?
when the bone marrow is unable to incorporate iron into hemoglobin. This may be either inherited or acquired.

Can a pregnant woman get the MMR vaccine while pregnant?
yes

Why are the carotid arteries auscultated for bruits?
this is indicative of generalized atherosclerosis

What is roseola?
a viral exanthem characterized by a high fever for 3 days then abrupt stopping of the fever and a maculopapular rash that blanches. also known as exanthem subitum.

What are signs indicative of a meningitis infection?
Kernig and Brudzinski’s signs

Cancer in the bone marrow that results in skeletal destruction
multiple myeloma

What is the average age of diagnosis of multiple myeloma?
65

a skin disorder that causes the nose to enlarge and become red, bumpy, and bulbous
rhinophyma

What are physical exam findings common in alcohol abuse?
tremors, macrocytosis (due to vitamin B12 and folate deficiencies common in alcoholics), hypertension, rhinophyma, peripheral neuropathy, teleangectasia, hepatosplenomegaly

What is the first sign of sexual maturation in a male?
an increase in testicular size (tanner stage 2)

The inability to name a familiar object
anomia

What happens to a womans vital signs when she is in her second trimester of pregnancy?
her blood pressure decreases

What is the most common cause of acute pharyngitis in children?
respiratory viruses

A depressed patient is started on an SSRI. When should another antidepressant be tried if there is no response?
8-12 weeks

If the number of bacteria on a urinalysis are greater than ________, this is indicative of a UTI.
100,000

What are signs of a ruptured TM other than the obviously ruptured TM?
muffled hearing and bright red blood in the canal

Osgood Schlatter disease produces pain where?
in the knees

Growing pains usually occur when?
at nighttime

Children with complaints of midbone pain should be worked for what MNM differential?
acute lymphocytic leukemia

NSAIDs should be used in caution with what patient population?
anyone with hypertension because they cause sodium retention and increase blood pressure

What is the most common cause of secondary dysmenorrhea?
endometriosis; symptoms include spotting in between periods, cervical stenosis or displacement, nodular or tender uterosacral ligaments

When should AAA screening be performed via US?
once for all males age 65-75 who have ever smoked

What is responsible for the transmission of poison ivy?
the oils from the plant itself. So the only way someone can pass it on to another person is if they still have oil from the plant on their skin (like if they haven’t bathed). Note that the fluid inside the blisters is not contagious

Actinic keratosis is a precursor for what?
squamos cell carcinoma

What is papilledema?
swelling of the optic nerve and disc secondary to increased ICP. Often co-occurring with a headache

Is sexual activity safe during pregnancy?
it can expose someone to STDs and it can also stimulate preterm labor due to stimulation of the lower uterine segment and release of oxtocin

A report of “knee locking” is a classic complaint of what?
a meniscal tear

Can a pregnant woman be on levothyroxine during pregnancy?
yes, she should continue it and have TSH checked monthly because she may need a higher dose as thyroid hormone needs increase during pregnancy

What characterizes mild persistent asthma?
asthma where symptoms occur more than twice weekly

People who do not have a spleen (asplenic) are at a greater risk of what?
more susceptible to bacterial infections

What 2 things put someone at the highest risk of developing pancreatitis?
gallstones and alcohol abuse. Hypertriglyceridemia can also cause it.

What are the RF for GI bleeding?
age 75 or older, warfarin use, daily NSAID use, chronic steroid use, PMHx of GI bleed

When two or more RF for a GI bleed are present, we should not start a patient on aspirin without what?
a daily PPI

What medication is first line for the treatment of asymptomatic bacteriuria or UTI in pregnancy?
nitrofurantoin

Athletic amenorrhea increases one’s risk of developing what?
osteoporosis; this is because there is a loss of body fat and body fat is what produces estrogen so estrogen levels decline

An intervention being performed to prevent the occurrence of the same event happening again is an example of _ prevention. Give an example.
secondary; taking a daily aspirin to prevent another stroke after already having one

What is Strattera (atomoxetine) used for?
ADHD; side effect includes increased BP and HR so monitor closely

What is the drug Danazol and what is it used for?
an androgen used in the treatment of endometriosis and fibrocystic breast disease

Danazol, an androgen, has what potential side effects?
edema, hirsutism, hair loss, vocal changes

The Mirena (Levonorgestrol) IUD stays in for how long?
5 years

What is the most common reason for persistent gonorrhea infections?
failure of the patient to abstain from unprotected sexual intercourse

What class of drug is theophylline? What does it do?
methylxanthine; it’s a bronchodilator

Beta blockers are contraindicated in which cardiovascular condition?
variant (prinzmetal) angina bc they may induce coronary vasospasm from unopposed alpha receptor activity

What class of drug is Ropinirole (requip) and what is it used for?
dopamine agonist; restless leg syndrome

Are males or females more likely to commit suicide?
males

How do depression vs. anxiety differ in the way that they affect sleep?
anxiety usually causes people to have problems falling asleep whereas depression causes early morning wakening

What is the most common cause of pneumonia in all ages?
strep pneumo

What is the most common cause of hemorrhagic stroke?
hypertension

What helps prevent infection by maintaining the acidic environment of the ear canal?
cerumen

Mortality associated with Kawasaki disease is most likely related to what?
coronary artery aneurysm

What is Kawasaki disease?
an acute febrile illness of early childhood characterized by vasculitis of the medium sized arteries, most noticeable in the coronary vessels

Serial echos must be performed in a patient with Kawasaki disease in order to rule out coronary artery aneurysms. When should these occur?
at the time of diagnosis, 1-2 weeks after onset of illness, 5-6 weeks after onset of illness

What is the most common cause of croup?
parainfluenza virus

What are the two subsets of impetigo?
bullous (fluid filled) or nonbullous (honey crusts)

Which protein is an important mediator of the inflammatory response and serves as a messenger at the site of antigen (allergen) invasion?
cytokines; they are released by mast cells in response to an invading antigen and recruit leukocytes and eosinophils

Paroxysmal events associated with abnormal electrical discharges of neurons in the brain
seizures

What is HELLP syndrome in pregnancy?
stands for hemolysis, elevated liver enzymes, and low platelets; is characterized by thrombocytopenia, hemolytic anemia, and liver dysfunction

HELLP syndrome in pregnancy is due to what?
endothelial dysfunction

Patients with acute coronary syndrome typically have plaque erosion caused by what?
accumulation of hyaluronan and neutrophils

Which diagnostic study is most helpful for differentiating Alzheimer’s disease from dementia with Lewy bodies?
PET scan

ADHD is a risk factor for both depression and what else?
substance abuse

Epididymitis with orchitis is commonly related to what?
genitourinary infections

Mycoplasma genitalium is most commonly associated with which disease presentation in men?
urethritis, especially if persistent or recurrent

C. trachomatis stands for what common type of bacteria infection?
chlamydia

Chlamydia passed from a mother to a newborn can result in which problems for the newborn?
conjunctivitis and pneumonia

In a patient with patent ductus arteriosus, where is the murmur best heard?
localized at the left clavicle and is both systolic and diastolic

What is the ductus arteriosus?
provides the fetus with a pathway from the pulmonary artery to the aorta in utero in order to skip the lungs

What are examples of some conditions that have multifactorial inheritance?
diabetes, obesity, arthritis, cancer, Alzheimers

Seborrheic dermatitis is basically the same thing as what?
eczema of the scalp

The flow of air coming in and out of the lungs in one inhalation and one exhalation
peak expiratory flow

What does an incentive spirometer measure?
peak expiratory flow

What happens in the luteal phase of the menstrual cycle?
LH and FSH decrease, the ruptured follicle closes after an egg has been released and forms the corpus luteum, which produces progesterone. Estrogen and progesterone remain high and it is those two things that cause the lining of the uterus to thicken further in preparation for fertilization

What is a sign of the initial appearance of measurable histamines in a patient with allergic rhinitis?
sneezing

The bacteria responsible for syphilis is called what?
treponema pallidum

The STI, chancroid, is caused by what responsible bacteria?
haemophilus ducreyi

What is the most common cause of septic arthritis?
staph aureus

The STI, mycoplasma genitalium, is unique in what way?
it lacks a cell wall and has a terminal tip-like structure which allows it to attach to and enter other cells. It then modulates the host’s immune response

What are the 3 secondary causes of type 2 diabetes?
prolonged physical or emotional stress, pregnancy, drugs such as steroids and hormonal contraceptives

How does hyperinsulinemia in PCOS work?
insulin resistance occurs in all places except for the ovary which remains sensitive to insulin. This insulin upregulates androgen production.

Which drug classes are responsible for causing urinary retention?
antihistamines, TCAs, antispasmodics, bronchodilators, antipsychotics, carbidopa levodopa

A 75 year old patient is experiencing progressive confusion and memory deterioration. Which condition mimics dementia that this patient should be tested for?
neurosyphilis

Which hormones in late pregnancy can block insulin and cause gestational diabetes?
cortisol, estrogen, and placental lactogen

Target shaped skin lesions as a result of a hypersensitivity reaction to certain infections and drugs
erythema multiforme

An abnormal growth of squamos epithelium in the middle ear and mastoid
cholesteatoma

The cremasteric reflex is assessed in infants for what purpose?
to assess for retractile testicles; this occurs when the reflex is too strong and it pulls the testicle out of the body and into the groin; this is normal and should go away by puberty

Patient populations who may present atypically when having a MI include who?
diabetics, females, elderly

A disorder that results in the destruction of platelets due to an autoimmune response
idiopathic thrombocytopenia purpura

Pelvic inflammatory disease is most commonly caused by what?
chlamydia and gonorrhea

A protruding abdominal mass after bending over, lifting, or coughing, and is painful with coughing, is often what in adults?
inguinal hernia

Hiatal hernias cause what type of symptoms?
GERD

What is the name of an immature female gamete?
oocyte

The fused ovum and sperm once fertilization has occurred
zygote

What are conditions that are often co-occurring with alopecia areata?
atopic dermatitis, vitiligo, thyroid disease, collagen-vascular diseases, Down syndrome

The medical term for eczema
atopic dermatitis

The leading cause of death in infants under the age of 1
sudden unexplained infant death

How is varicella zoster transmitted?
via the respiratory tract

The presence of pruritic papules, macules, and vesicles in various stages of healing
varicella zoster

What is presbycusis?
age related hearing loss

Age is the most common cause of presbycusis, but what other conditions may play a role in quickening the onset of this?
white, infections, smoking, hypertenson, diabetes, vascular disease, immune disorders, hormonal factors

The fascia layer of the male anatomy that the anterior 2/3s of the testicle resides in
tunica vaginalis

A subtype of strabismus that describes an inward turning of the eye
esotropia

The abducens nerve (CN VI) is responsible for what?
lateral movement of the eye outward

The trochlear nerve is responsible for what extraocular movement?
down and inward movement

Why is primary open-angle glaucoma considered a chronic glaucoma?
there is a SLOW rise in intraocular pressure

A benign epidermal tumor that is a well-demarcated, coin-like, pigmented lesion with a stuck on appearance
seborrheic keratosis

The most common precancerous skin lesion that results from years of repeated sun exposure
actinic keratosis

What happens during the follicular phase of the menstrual cycle?
FSH and LH increase which stimulate the production of estrogen. Ultimately, it is estrogen that prepares the uterus for ovum fertilization

A superficial dermatophyte/fungal infection of the skin of the scalp, eyebrows, and eyelashes
tinea capitis

Bacterial invasion of the renal parenchyma
pyelonephritis

What is phimosis vs. paraphimosis?
phimosis is tightening of the foreskin over the glans that prevents retraction; paraphimosis is when you can retract the foreskin but you can’t pull it back up

What is a common characteristic of a person with Graves disease?
ophthalmopathy causing lymphocytes to infiltrate the extraocular muscle, resulting in paralysis of EOMs, involvement of the optic nerve, and corneal ulcers

Which phase of the menstrual cycle begins with a surge in LH and FSH?
ovulatory phase

What is the pathophys of HIV?
causes destruction of the CD4 T cells resulting in eventual immune suppression

Cells within the epidermis that are primarily responsible for protecting the skin from UV rays in sunlight
melanocytes

Body lice primarily live where?
on bedding and clothing, not people

Body lice are vectors for which diseases?
epidemic typhus, trench fever, relapsing fever

Fifth disease is spread via how?
respiratory droplets

What are other names of fifth disease?
parvovirus, slapped cheek disease

What is the life span of lice?
30 days

The hypersensitivity and pain crescendo experienced in conjunction with a migraine is thought to be related to the release of what?
substance P; a neurotransmitter which functions as the pain transmitter of the dorsal horn and is responsible for causing nausea, vomiting, stress, and anxiety

Where is the location of the tricuspid valve?
separates the right atrium and ventricle

What does a tricuspid regurgitation murmur sound like?
best heard at the left sternal border, on both systole and diastole. Increases with inspiration

When can you hear the murmur associated with pulmonic stenosis?
mid-late systolic murmur

When can you hear the murmur associated with aortic regurg?
diastole only

When can you hear the murmur associated with mitral valve stenosis?
diastole only

What EKG changes may be present during episodes of angina?
transient ST elevation, T wave changes such as inversions, ST depressionals, Q waves

Children and teens present with depression most commonly how?
irritability

Are the sickling of RBCS in sickle cell anemia reversible?
initially, yes they are reversible with oxygenation. But repeated episodes cause the cells to become irreversibly sickled.

When the brain is exposed to something rewarding, it responds by increasing the release of what?
dopamine

Where are T cells produced?
in the thymus

Where are B cells produced?
in the bone marrow

What is the pathophys behind a thyrotoxic crisis (aka thyroid storm)?
T3 and T4 are overproduced which leads to increased production of epinephrine and severe hypermetabolism

What causes a reduction in the number of RBCs in pregnancy?
iron deficiency anemia due to blood volume expansion and a decrease in hemoglobin levels so the iron stores are depleted because they are needed to be used for the expanded blood volume

When should the ductus arteriosus close in an infant?
within the first 1-2 days of birth

The minimum arterial pressure exerted during relaxation and dilation of the ventricles
diastole

Lyme disease is caused by what spirochete present on ticks?
borrelia burgdorfei

What are the potential sequelae of strep pharyngitis?
acute glomerulonephritis, peritonsillar abscess, toxic shock disease, rheumatic heart disease (although rare)

The medical term for pubic lice aka crabs
phthirus pubis

Petechiae noted on the cervix during a pelvic exam is a sign of what disease process?
trichomoniasis; also called “strawberry cervix”

What is the difference between a folliculitis and a furuncle?
folliculitis is an inflammation of the follice whereas a furuncle is an abscess that results from folliculitis

Urea is eliminated by the kidneys, but where does it come from originally?
from the liver as a byproduct of protein metabolism

What are the 5 primary structures of the immune system?
lymph nodes, thymus, tonsils, spleen, bone marrow

Bacteria most commonly responsible for pyelonephritis
e coli

What causes back pain in pregnancy?
curvature of the lumbosacral vertebrae

What is dacrocystitis?
inflammation of the nasolacrimal duct due to duct obstruction or infection

What are potential causes of blepharitis?
bacterial infection, dry eyes, rosacea

What are s/s of croup?
hoarseness, cough, inspiratory stridor, possible respiratory distress due to narrowing of the larynx

Women who become pregnant later in life have an increased risk of what?
breast cancer

What are things women can do to decrease their risk of breast cancer?
regular physical activity, breastfeeding

Does an increase or decrease in blood pH affect the rate and degree of sickling in sickle cell anemia?
a decrease in blood pH increases the rate

What is the difference between Prinzmetals and stable (classic angina)?
Prinzmetals may occur randomly and while at rest, whereas stable angina is usually only with physical activity

Why may infection of the palatine tonsils become serious very quickly?
the area is composed of loose connective tissue

What are cutaneous xanthomas?
localized lipid deposits caused by elevated lipids or LDL

Uterine prolpase is caused by stretching of the uterine __
ligaments

What causes bacterial vaginosis?
a decrease in lactobacillus species within the vagina

Where is acanthosis nigricans most likely to occur?
axillae, neck, groin

What causes subjective tinnitus?
abnormal neuronal activity

HIV produces cellular immunity deficiency by depleting what?
helper T cells

What is the function of B cells in the immune system?
development of antibodies

When does the male fetus begin to produce testosterone and how?
around 9 weeks gestation due to the Leydig cells

What is the pathophys of Addison’s disease?
causes decreased or absent aldosterone levels resulting in increased excretion of sodium and water by the kidneys, and hyperkalemia

What is the most serious complication of Addison’s disease?
acute adrenal insufficiency or adrenal crisis

What are the 4 heart defects of Tetralogy of Fallot?
VSD, right ventricular hypertrophy, overriding aorta, pulmonary stenosis

What are the s/s of Kawasaki disease?
think CREAM; conjunctivitis, rash, erythema of hands and soles of feet, adenopathy (cervical), mucous membranes (strawberry tongue)

A palpable softening of the cervical isthmus during pregnancy
Hegar’s sign

A bluish tint to the vagina and cervix due to increased vascularity during pregnancy
Chadwick’s sign

What is Paget’s disease?
where there is abnormal bone destruction or growth of bone. It is also a malignant disease of the breast.

Does Meniere’s disease result in hearing loss?
yes, gradual but progressive sensorineural hearing loss

What is another term for chronic bladder pain syndrome?
interstitial cystitis

What classifies someone as having “prediabetes”?
hgba1c between 5.7 and 6.4

What classifies someone as having diabetes?
hgba1c 6.5 or greater

A reduction in vision in one or both eyes causing loss of binocular vision
amblyopia

What is Brudzinski’s sign?
the patient lies supine and the NP flexes the patients neck forward. If both hips and knees flex at the same time, this is indicative of meningitis

A child presents with erythematous papules and vesicles, that are weeping, oozing, and crusty. They are located all over the forehead, wrists, elbows, and backs of knees. What is this most likely to be?
atopic dermatitis

In older adults, what is an audible S3 sound usually a sign of?
left ventricular hypertrophy from heart failure, or cardiomyopathy

How is cervical radiculopathy different from cervical myelopathy?
in radiculopathy, there is nerve root compression that results in burning pain and n/t in the neck and one arm. In myelopathy, there is pain with bilateral weakness and n/t in both the upper and lower extremities

Other than scratching the medial aspect of the thigh, how else can we elicit the cremasteric reflex in a child?
have them sit cross legged and blow into a balloon. This will increase intraabdominal pressure and stimulate the reflex.

What is the Lachman’s test and what does it identify?
used to assess for ACL tear; the knee is held passively at 30 degrees flexed and then one hand stabilizes the femur while the other applies a gentle anterior force to the proximal tibia. If it moves beyond it’s normal ROM, there may be an ACL tear

When should the testicles fully descend into the scrotum by in an infant?
6 months of age. If not descended by this time, then refer to Urology at 6 months although surgical correction (orchipexy) may not be performed until 1 year

What is another name for the moro reflex?
the startle reflex; both arms should extend outwards when this is positive

If a moro reflex in an infant is only positive in one arm, then what do you need to consider?
examine the clavicle for a potential fracture

Which model is used to designate risk factors for melanoma?
think HARMM; history, age, regular dermatologist absent, mole changing, male gender

What is a sign of an ankle fracture on physical exam?
point tenderness over the posterior malleolus with an inability to bear weight after 4 or more steps

What is an acoustic neuroma?
something pressing, likely a tumor, on the acoustic nerve that results in dizziness, loss of balance, facial numbness, hearing loss, and tinnitus

The axillary lymph nodes drain lymphatic fluid from where?
breast, upper abdomen, upper back, pectoral region, and upper limbs

International travelers to endemic areas are at a risk for what form of hepatitis?
hepatitis A because it can be transmitted through contaminated food or drink

Adrenarche is the early presence of pubic hair in girls aged __
5-8 years old

A condition that presents with symptomatic limb ischemia upon exertion is termed:
atherosclerotic peripheral arterial disease

The largest salivary gland is the parotid gland, and where does it drain to?
Stensen’s duct which has an opening on the buccal mucosa opposite the second molar

The varus stress test assesses for a tear in which part of the lower extremities?
lateral meniscus

The valgus stress test assesses for a tear in which part of the lower extremities?
medical meniscus

To evaluate the uterus during a bimanual exam, the examiner would lubricate the index and middle fingers of one hand and insert them into the vagina. The other hand would be placed on the abdomen where?
about midway betwee the umbilicus and symphysis pubis while elevating the cervix and uterus with the other hand

A feeling of constantly needing to pass stool
tenesmus

Severe constipation resulting from intestinal obstruction
obstipation

What does the vaginal discharge associated with trich look like?
profuse, yellowish green that is malodorous

What does the discharge associated with bacterial vaginosis look like?
gray or white, thin, malodorous (fishy) and not profuse

The nurse practitioner instructs the patient to place on hand behind his back and touch his shoulder blade. This shoulder movement elicits what?
internal rotation

How do we test for flexion and extension of the shoulder?
extension is asking the patient to move their arm behind themself. Flexion is asking the patient to move their arm in front of the body

Symptoms related to Shaken Baby Syndrome are due to what?
uncontrollable cerebral edema and hypoxia

What are the symptoms of Shaken Baby Syndrome?
blindness, inability to perform previously learned milestones, flaccid muscle tone

Koplik’s spots are indicative of what disease?
measles (rubeola)

The medical term for measles
rubeola

What do Koplik’s spots of measles look like?
small white specks that resemble grains of salt on a red background

Round or oval shaped lesions surrounded by erythematous mucosa found anywhere on the oral mucosa
aphthous ulcers

Excessive or prolonged menstrual flow occurring at regular intervals
menorrhagia

Intermenstrual bleeding (aka spotting in between periods)
metrorrhagia

Polymenorrhea is when there are fewer than __ between periods
21 days

Oligomenorrhea is when there are more than _ between periods; or only 4-9 menstrual cycles per year
35 days

Retraction of the nipple and areola are suggestive of what?
an underlying breast mass; this is never considered normal

What is the straight leg raise test?
used to evaluate for sciatica; the NP raises the straight leg while flexing the hip and then dorsiflexes the foot. Positive if pain is elicited.

What is Tinel’s sign?
positive for carpal tunnel; the NP taps over the median nerve and is positive if n/t is felt

What is Phalen’s sign?
positive for carpal tunnel; patient holds their wrists together to form right angles for 60 seconds and is positive if n/t is felt

Test used to identify de Quervain’s tenosynovitis
Finkelsteins test

Test of thumb movement by instructing the patient to place his thumb in the palm and then move the wrist toward the midline in ulnar deviation
Finkelsteins test

What does the murmur associated with mitral regurg sound like?
pansystolic, harsh murmur heard loudest at the apex with radiation toward the left axilla

When auscultating the apex of the heart in a child older than 7, the bell of the stethoscope should be placed where?
fifth intercostal space to the left of the midclavicular line; if younger than 7, it is best heard at the third or fourth intercostal space

What is the main sign of Kaposi’s sarcoma?
raised or flat deep purple lesions in the mouth

Where do lesions of Kaposi’s sarcoma usually manifest?
in the mouth, GI tract, or lungs

A patient is experiencing a dull achy pain in the epigastric area with eating. This type of pain is consistent with what?
a gastric ulcer

How is the pain of a gastric ulcer vs. a duodenal ulcer different?
the pain is worsened with eating with a gastric ulcer but improved with eating in a duodenal ulcer

What are s/s of glaucoma?
loss of peripheral vision, halos around lights, difficulty focusing on near objects

Higher level functioning, such as using the telephone, doing laundry, taking medicine, etc. are considered to be called what?
instrumental activities of daily living

An inability to extend the knee is a sign of what?
a partial or complete patellar tendon tear

Which part of the spine controls the ankle DTRs?
sacral nerve 1

Which part of the spine controls the knee DTRs?
lumbar nerves 2, 3, 4

Which part of the spine controls the biceps DTRs?
cervical nerves 5 and 6

Which part of the spine controls the triceps DTRs?
cervical nerves 6 and 7

What are s/s of carpal tunnel syndrome?
dropping objects, unable to twist lids off of jars, aching at the wrist or forearm, numbness of the first 3 digits of the hand

Which movement indicates a nuchal rigidity sign when working a patient up for meningitis?
neck stiffness and resistance when flexing the neck forward

What is Kernig’s sign?
flex the patients leg at both the hip and the knee, then straighten the knee. Pain and resistance to extension of the knee are positive for meningitis.

A patient who is unable to touch his left scapula with his right hand likely has what?
a rotator cuff tear

A widened pulse pressure greater than or equal to 60 in an older adult is a risk factor for what?
cardiovascular disease, stroke, renal disease

The ethmoidal sinuses are located where?
between the eyes

Where do the sphenoid sinuses lie?
just behind the ethmoid sinuses

Where do the maxillary sinuses lie?
around the nasal cavity

What describes a stage III pressure ulcer?
full thickness tissue loss and subcutanous fat may be present, but bone, tendon, or muscle are not exposed

Dislocation of the elbow joint caused by the sudden pull on the extended pronated forearm
nursemaid’s elbow

Localized tenderness over the ankle joint is a sign of what?
a ligamentous injury; point tenderness and inability to bear weight is more of a sign of an ankle fracture

Describe renal adaptation of the newborn
the kidneys are structurally complete but physiologically immature. the infant is at increased risk of metabolic acidosis due to the kidneys inability to concentrate urine and adapt to fluid and electrolyte stress

Where is the best place to locate the twelfth rib?
between the spine and lateral chest

What is biliary colic?
pain in the epigastric region or RUQ that radiates to the right scapula or shoulder; indicative of cholecystitis

Costochondritis occurs when there is inflammation of the cartilage where?
that connects the ribs to the sternum

What aggravates costochondritis?
movement of the chest, trunk, and arms

Which segments of the spine control the plantar reflexes?
lumbar 5 and sacral 1

A softening of the skin at the angles of the mouth which may be due to nutritional deficiency
angular cheilitis

Angular cheilitis can be caused by what?
nutritional deficiency

What causes actinic cheilitis?
excessive exposure to sunlight; most often affects the lower lip

Intention tremors appear with movement and worsen when?
as the target gets closer

Nausea, diaphoresis, and pallor triggered by a fearful or unpleasant event
vasovagal syncope

Which conditions are known to cause polyuria?
lithium toxicity, uncontrolled diabetes, disorders of the posterior pituitary and hypothalamus (hypogonadism), and hypokalemic nephropathy

Breath sounds heard over the periphery of the lung fields are what?
vesicular; they are quiet and wispy

What do bronchovesicular breath sounds sound like?
full inspiratory phase with a shortened and quieter expiratory phase

Thenar atrophy suggests what?
a median nerve disorder

Does the ulnar nerve innervate the pinky or the thumb?
pinky

The pregnant woman who has a BMI of less than 18.5 should gain how many pounds in pregnancy?
28-40 pounds

The pregnant woman who has a BMI of 18.5-24.9 (normal) should gain how many pounds in pregnancy?
25-35 pounds

The pregnant woman who has a BMI of 25-29.9 (overweight) should gain how many pounds in pregnancy?
15-25 pounds

The pregnant woman with a BMI over 30 should gain how many pounds in pregnancy?
11-20 pounds

A BMI of less than _ is considered underweight
18.5

The term used to refer to skin that is peeling
exfoliation

What will a basal cell carcinoma on the eyelid look like?
papule with an ulcerated center, most often on the lower lid and medial canthus

What is Rovsing’s sign?
positive for appendicitis; palpation on the LLQ elicits pain in the RLQ

What causes plantar warts?
human papillomavirus; usually occur on the sole of the foot

In second degree uterine prolapse, where is the cervix located?
at the introitus

In third degree uterine prolapse, where is the cervix located?
both the cervix and vagina are outside the introitus

The anterior cervical lymph node chain is located where?
anterior and superficial to the sternocleidomastoid muscle

How do we diagnose a migraine headache?
if 3 of the 5 POUND symptoms are present: pulsatile or throbbing, one day duration or 4-72 hours if left untreated, unilateral, nausea or vomiting, disabiling or intense causing interruption of daily activity

What causes the S4 sound?
the atrium forcefully contracting against a stiffened ventricle

During the vaginal exam of a pregnant woman in her first trimester, an adnexal mass with tenderness is palpated. This is consistent with what?
an ectopic pregnancy

Stridor indicates a partial or complete obstruction of the _ and is best heard where?
larynx; neck

When assessing an african american person, black, dusky mucous membranes are related to what
cyanosis

Persistent, sharp, and knife-like chest pain is indicative of what?
pericarditis or pleuritic chest pain

Thin, pencil-like stool can be associated with what?
a lesion in the sigmoid colon

An acute viral illness that presents with a burning retrosternal discomfort and a dry cough is suggestive of what?
tracheobronchitis

The shiny, pink area located around the cervical os is known as what?
squamos epithelium

Tenderness of the posterior medial malleolus may be a sign of what?
tibial tendinitis

When performing a rectal exam on a female, a hard nodular rectal “shelf” is palpable at the tip of the examiner’s finger. What is this suggestive of?
metastatic tissue in the rectouterine pouch

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