Final Exam: NR 565 / NR565 Advanced
Pharmacology Exam Review | Weeks 5-8
Covered| Guide with Questions and Verified
Answers (2023/ 2024)
Q: DTaP or Tdap
o Who should receive the Tdap vaccine?
Answer:
Teens and adults after receiving full
DTaP course during childhood
Q: Vaccine Contraindications
o True contraindication for DTaP or Tdap vaccine.
Answer:
Moderate to severe febrile illness
Hx of post-vaccination anaphylactic reaction (immediate) or encephalopathy within
7 days
Caution: if prior vaccination produced a shock-like state, fever over 105 within 48 hours,
persistent inconsolable crying within 48 hours lasting for 3 hours, or seizures within 3 days.
Q: Vaccine Contraindications
o Varicella
Answer:
Pregnancy, certain cancers, hypersensitivity to neomycin or gelatin, immunocompromised.
Children should avoid salicylates for 6 weeks after
Q: Vaccine Contraindications
o Hepatitis B virus (HBV) vaccine
Answer:
Prior anaphylactic reaction to vaccine or baker’s yeast
Q: Examples of vaccine types
o Attenuated
Answer:
MMR, varicella, rotavirus, influenza (intranasal)
Q: Examples of vaccine types
o Live virus
Answer:
MMR, varicella, rotavirus, influenza
Q: Examples of vaccine types
o Toxoid
Answer:
Dtap
Q: Examples of vaccine types
o Inactive viral antigen
Answer:
Polio, Hep A and B, influenzas (inactivated)
Q: Types of immunity
o What are they and how is each one achieved?
Answer:
Herd/community – when a large group of people is immune
Active – when responding to either real infection or vaccination
Passive – transmitted from mother to baby or via antibodies
Natural immunity – nonspecific, such as physical barriers, NK cells, etc.
Acquired immunity – specific after exposure to a foreign substance, produce anti- gens
Cell-mediated immunity – immune response where targets are attacked directly by cells
Humoral immunity – immunity response medicated by antibodies
Q: Definition of vaccine
Answer:
o a preparation containing whole or fractionated mi- croorganisms. Administration causes the
recipient’s immune system to manufacture antibodies directed against the microbe from which
the vaccine was made
Q: Post exposure prophylaxis for suspected rabies bite
Answer:
o 4 doses of vaccine
- 1ml IM on days 0,3,7,14, with RIG (rabies immune globulin) given on day 0.Those who have
previously been vaccinated, 2 doses are given on days 0 and 3, no RIG
Q: Patient teaching and assessments for post vaccine side effects
Answer:
o Vaccine Information Statement (VIS) on administered vaccines, Administer Tylenol to the
patient before discharge, discuss reactions for administered vaccines, provide a schedule for
upcoming vaccine doses, have patient wait 15 minutes before dis- charge
Q: Who can receive attenuated influenza vaccine (FluMist)?
Answer:
o Healthy
non-pregnant patients ages 2 49, with no hx of previous reactions to this vaccine, not
immunocompromised or caring for someone who is. Contraindicated in kids with asthma or kids
receiving meds with salicylates.
Q: Pantoprazole
-common doses (calculations to figure quantity)
-directions for use
-indication
Answer:
o Common Doses:
20 and 40mg delayed-release tablets and 40mg enteric-coated granules
o Directions for use:
Monitor for pain relief and eradication of H. pylori infection. When used long term, there is an
increase for osteoporosis and fractures = maintain an adequate intake of calcium and vitamin D,
and inform patients about symptoms of hypomagnesemia, including muscle cramps, palpitations,
and tremors
o Indication:
Gastric and duodenal ulcers, as well as GERD
Q: Metronidazole
-common doses (calculations to figure quantity)
-directions for use
-indication
Answer:
o Common Doses:
500mg three times a day for 10-14 days
o Directions for use:
The most common side effect is nausea and headache. A disulfiram-like reaction can occur if
used with alcohol and it should also not be taken during pregnancy.
o Indication:
H. pylori treatment (very effective against sensitive strains of H. pylori
Q: Ondansetron
-common doses (calculations to figure quantity)
-directions for use
-indication
Answer:
o Common Doses: