NR 565 / NR565 Advanced Pharmacology Final Exam

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  1. Whatiisitheiexpectedionsetiofiinsuliniglarginei(U-100):i
    ~ 70
  2. Withihowimanyiminutesiofiaimealishouldiinsulinilisproi(Humalog)ibeiadministered?i
    ~ 15ibeforeiaimeal
  3. whenimightiinsulinineedsiincrease?i
    ~ infectionisevereistress
    ~ pregnancyisteroids
    ~ growthispurtsiforiadolescents
  4. whatiareisomeifactorsithatimayiresultiinihypoglycemia:i
    ~ increasediexerciseivomitingi/idiarrhea
    ~ increasedifoodiintakeialcohol
  5. WeineeditoieducateiouripatientsiwithidiabetesionitheiS/Siofihypoglycemia,iwhatiareithe
    y?i
    ~ Sweatingi
    ~ dizzinessiconfusioni
    ~ palpitationsi/iincreasediHRi
    ~ shakinessianxietyiheadachei
    ~ coma,iconvulsions,ideathialteredimentalistatus
    1 / 3
  6. Whatimedicationsimightimaskitheisignsiofihypoglycemia:i
    ~ BetaiBlockers
  7. aibloodiglucoseilessithaniwhatiisiconsideredihypoglycemia:i
    ~ <70
  8. WhatiisitheiMOAiofimetformin:i
    ~ decreasesiglucoseiproductioniinitheiliver
    ~ increasesitissueiresponseitoiinsulin
  9. Whatiareitheicommoniadverseieffectsiofimetformin:i
    ~ GIiupset
    ~ N/V/D
    ~ decreasediappetiteiweightiloss
    ~ lacticiacidosis
  10. Whatiisitheiblackiboxiwarningiforimetforminiandiwhatiareitheisigns?i
    ~ Lacticiacidosis
  11. Isimetforminiaigoodichoiceiforipatientsiwhoiskipimeals?i
    ~ Yes,ihasiloweripotentialiinicausingihypoglycemia
  12. howiwouldimanagementiofisideieffectsiofimetformin?i
    ~ startilowiandititrateiup
    ~ educateithatisymptomsicanibeihardiforitheifirsticoupleiofiweek
    2 / 3
  13. whatiS/Siwouldiyouieducateipatientsitoibeiawareiofiforipotentialilacticiacidosisidiagnosi
    s:i
    ~ hyperventilation
    ~ myalgiailethargy
  14. Whoiisiatiriskiforilacticiacidosis:i
    ~ kidneyifailure/ikidneyiissuesiheartifailureipatients
    i
  15. Besidesidiabetes,iwhatiisimetforminiuseditoitreat:i
    ~ PCOS
  16. whatikindiofideficiencyiareipatientsiwhoiareitakingimetforminiatiriskifor?i
    ~ foliciacid
    ~ B12
  17. isimetforminiaigodioptioniforipatientsiwithiHF?i
    ~ contraindicatedidueitoilacticiacidosis,itheyiareiatihigheririsk
  18. Isimetforminiorisulfonylureasimoreilikelyitoisignificantlyidropiaipatientsibloodisugar?i
    ~ Sulfonylureas
    ~ theyiareiknowniforidroppingibloodisugars,iorihypoglycemicievents
  19. Ifipatientiisionimetforminiandiisischedulediforisurgeryioritoiuseicontrastidye,iwhatiisiind
    icated?iwhatiisiindicatedibeforeiresumingitreatment?i
    ~ Holdidayiofitheitest,ianditheni48ihoursiafteriimaging
    ~ beforeiresumingimetforminitestiforiCRiclearance

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