A nurse is providing teaching for a client who is taking isoniazid (INH) for tuberculosis

A nurse is providing teaching for a client who is taking isoniazid (INH) for tuberculosis. Which of the following statements by the client indicates an understanding of the teaching?

A.
This medication may cause my blood pressure to increase.”

B.
“I should take an antacid with each dose of this medication.”

C.
“I plan to take this medication for 1 week.”

D.
“I will have my liver function tested while I am taking this medication.”

The correct answer and Explanation is :

The correct answer is:

D. “I will have my liver function tested while I am taking this medication.”

Explanation:

Isoniazid (INH) is a key medication used in the treatment of tuberculosis (TB). It is important for patients to be educated about its potential side effects and necessary precautions to ensure effective and safe treatment. Here’s an explanation of why option D is the correct response:

  1. Liver Function Monitoring (Option D):
    Isoniazid is metabolized by the liver and has the potential to cause hepatotoxicity (liver damage). Regular monitoring of liver function is crucial to detect any signs of liver damage early. This monitoring typically involves periodic liver function tests (LFTs) to check for elevated liver enzymes. Clients on INH should understand the importance of this monitoring to prevent serious liver complications.
  2. Blood Pressure Concerns (Option A):
    Isoniazid is not typically associated with significant changes in blood pressure. Therefore, stating that it might cause blood pressure to increase indicates a misunderstanding of the medication’s side effects.
  3. Antacids (Option B):
    Isoniazid can interact with antacids. Antacids containing aluminum or magnesium can reduce the absorption of isoniazid, potentially decreasing its effectiveness. It is generally recommended to take antacids at least 1-2 hours apart from isoniazid to avoid this interaction.
  4. Duration of Treatment (Option C):
    Tuberculosis treatment with isoniazid usually lasts for at least 6-9 months, not just 1 week. The treatment duration is crucial to effectively eradicate the TB bacteria and prevent resistance. Taking the medication for only a week is inadequate and can lead to incomplete treatment and drug-resistant TB.

In summary, monitoring liver function is an essential aspect of managing isoniazid therapy due to the risk of hepatotoxicity, making option D the correct statement indicating understanding of the medication’s management.

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